Michael N Robertson Selected Research

uprifosbuvir

1/2019	Efficacy and safety of ruzasvir 60 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4 or 6 infection.
1/2019	Efficacy and safety of a two-drug direct-acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6.
11/2017	Safety and efficacy of an 8-week regimen of grazoprevir plus ruzasvir plus uprifosbuvir compared with grazoprevir plus elbasvir plus uprifosbuvir in participants without cirrhosis infected with hepatitis C virus genotypes 1, 2, or 3 (C-CREST-1 and C-CREST-2, part A): two randomised, phase 2, open-label trials.
11/2017	Safety and efficacy of a fixed-dose combination regimen of grazoprevir, ruzasvir, and uprifosbuvir with or without ribavirin in participants with and without cirrhosis with chronic hepatitis C virus genotype 1, 2, or 3 infection (C-CREST-1 and C-CREST-2, part B): two randomised, phase 2, open-label trials.

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Michael N Robertson Research Topics

Disease

34	Infections 01/2021 - 04/2004
8	Chronic Hepatitis C 11/2020 - 07/2015
8	Fibrosis (Cirrhosis) 01/2020 - 08/2014
7	HIV Infections (HIV Infection) 01/2013 - 07/2003
3	Fatigue 01/2019 - 09/2007
3	Mycoses (Diseases, Fungus) 12/2017 - 07/2014
2	Headache (Headaches) 01/2019 - 09/2007
2	Virus Diseases (Viral Diseases) 01/2019 - 02/2003
2	Coinfection 11/2017 - 08/2015
2	Hepatitis C 10/2017 - 01/2016
2	Viremia 03/2008 - 04/2004
1	Chronic Renal Insufficiency 11/2020
1	Cellulitis 01/2018
1	Insulin Resistance 01/2018
1	Chest Pain (Chest Pains) 01/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Opiate Overdose 01/2018
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2017
1	Abscess 11/2017
1	Keratitis 11/2017
1	Pain (Aches) 03/2014
1	Malaria 01/2012
1	Tuberculosis (Tuberculoses) 01/2012
1	Communicable Diseases (Infectious Diseases) 01/2012
1	Disease Progression 04/2011
1	HIV Seropositivity 12/2008
1	Diarrhea 09/2007
1	Nausea 09/2007
1	Hematuria 09/2007
1	Hyperbilirubinemia 09/2007
1	Abdominal Pain (Pain, Abdominal) 09/2007
1	Flank Pain 09/2007
1	Hyperlipidemias (Hyperlipidemia) 07/2003

Drug/Important Bio-Agent (IBA)

20	grazoprevirIBA 12/2020 - 08/2014
18	elbasvirIBA 12/2020 - 07/2015
13	VaccinesIBA 01/2013 - 04/2004
10	Ribavirin (Virazole)FDA LinkGeneric 01/2020 - 08/2014
8	Antiviral Agents (Antivirals)IBA 12/2020 - 09/2015
6	Pharmaceutical PreparationsIBA 01/2019 - 09/2007
5	InterferonsIBA 01/2019 - 07/2015
4	uprifosbuvirIBA 01/2019 - 11/2017
4	ruzasvirIBA 01/2019 - 11/2017
4	RNA (Ribonucleic Acid)IBA 11/2017 - 04/2011
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2017
3	posaconazole FDA Link 12/2017 - 07/2014
3	Protease Inhibitors (Protease Inhibitor)IBA 01/2016 - 07/2003
2	Lamivudine (Epivir)FDA Link 01/2021 - 07/2003
2	Opioid Analgesics (Opioids)IBA 11/2020 - 11/2016
2	DNA VaccinesIBA 03/2014 - 03/2008
1	NucleosidesIBA 01/2021
1	doravirineIBA 01/2021
1	islatravirIBA 01/2021
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2021
1	Drug CombinationsIBA 01/2019
1	Oral ContraceptivesIBA 01/2019
1	NucleotidesIBA 01/2019
1	Ethinyl Estradiol (Estinyl)FDA LinkGeneric 01/2019
1	CreatinineIBA 01/2018
1	SofosbuvirIBA 01/2018
1	Proton Pump InhibitorsIBA 10/2017
1	SimeprevirIBA 09/2015
1	telaprevirIBA 09/2015
1	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 09/2015
1	CyclodextrinsIBA 07/2014
1	SolutionsIBA 07/2014
1	Phosphates (Orthophosphate)IBA 03/2014
1	EpitopesIBA 01/2013
1	AntibodiesIBA 07/2012
1	AIDS VaccinesIBA 07/2012
1	Viral RNAIBA 02/2012
1	SAIDS VaccinesIBA 02/2012
1	CytokinesIBA 11/2008
1	DNA (Deoxyribonucleic Acid)IBA 04/2004
1	Protein Subunits (Protein Subunit)IBA 04/2004
1	Zidovudine (Retrovir)FDA LinkGeneric 07/2003
1	Triglycerides (Triacylglycerol)IBA 07/2003
1	Indinavir (Crixivan)FDA Link 07/2003
1	AntigensIBA 02/2003

Therapy/Procedure

9	Therapeutics 11/2020 - 07/2003
1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2019
1	Highly Active Antiretroviral Therapy (HAART) 09/2007
1	Aftercare (After-Treatment) 07/2003